引用艾基生物服务及产品高分文献精选
*点击文献标题可查看原文
*点击所引用的服务/产品可查看对应服务/产品的介绍
[1] A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism.
发表于:iScience. 2022. PMCID: PMC9249674 IF=6.107
引用服务/产品:克隆构建、基因合成
[2]Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.
发表于:Genomics Proteomics Bioinformatics. 2021. PMCID: PMC8578027 IF=6.409
引用服务/产品:基因合成、小RNA测序
[3]Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression.
发表于:J Exp Clin Cancer Res. 2020 PMCID: PMC7203840 IF=13.801
引用服务/产品:克隆构建、RNA合成
[4]SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury
发表于:iScience. 2021 PMCID: PMC8169952 IF=6.107
引用服务/产品:克隆构建
[5]BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma.
发表于:Cell Biosci. 2022 PMCID: PMC8932231 IF=9.584
引用服务/产品:慢病毒包装、克隆构建
[6]circ-NOL10 regulated by MTDH/CASC3 inhibits breast cancer progression and metastasis via multiple miRNAs and PDCD4.
发表于:Mol Ther Nucleic Acids. 2021 PMCID: PMC8526500 IF=10.183
引用服务/产品:克隆构建、RNA合成
[7]A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes.
发表于:Nat Commun. 2021 PMCID: PMC8087678 IF=17.694
引用服务/产品:siRNA合成
[8]Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis.
发表于:Cell Mol Life Sci. 2022 PMCID: PMC9391247 IF=9.207
引用服务/产品:克隆构建
[9]Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model.
发表于:Cell Death Dis. 2022 PMCID: PMC9293975 IF=9.685
引用服务/产品:慢病毒包装、克隆构建
[10]Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation.
发表于:EBioMedicine. 2019 PMCID: PMC6838432 IF=11.205
引用服务/产品:环状RNA载体构建
[11]CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1.
发表于:Theranostics. 2022 PMCID: PMC9274740 IF=11.6
引用服务/产品:siRNA合成
[12]Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
发表于:Cell Death Dis. 2022 PMCID: PMC9132929 IF=9.685
引用服务/产品:细胞株鉴定
[13]AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
发表于:Nucleic Acids Res. 2022 PMCID: PMC9122597 IF=19.16
引用服务/产品:普通引物合成、Qubit dsDNA HS Assay mix Kits
[14]Generation of individualized immunocompatible endothelial cells from HLA-I-matched human pluripotent stem cells.
发表于:Stem Cell Res Ther. 2022 PMCID: PMC8812039 IF=8.079
引用服务/产品:细胞株鉴定
[15]INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
发表于:J Exp Clin Cancer Res. 2022 PMCID: PMC8740451 IF=13.801
引用服务/产品:克隆构建
[16]P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer.
发表于:Cancer Commun (Lond). 2021 PMCID: PMC8696220 IF=15.283
引用服务/产品:细胞株鉴定
[17]MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1.
发表于:Cells. 2020 PMCID: PMC7140536 IF=7.666
引用服务/产品:克隆构建、基因合成
[18]D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration.
发表于:Signal Transduct Target Ther. 2020 PMCID: PMC7054264 IF=38.104
引用服务/产品:克隆构建、基因合成
[19]A sensitive, accurate, and high-throughput gluco-oligosaccharide oxidase-based HRP colorimetric method for assaying lytic polysaccharide monooxygenase activity
发表于:Biotechnol Biofuels Bioprod. 2022 PMCID: PMC8830019 IF=7.67
引用服务/产品:克隆构建、基因合成
[20]Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4+ T cells.
发表于:Stem Cell Res Ther. 2022 PMCID: PMC8818240 IF=8.079
引用服务/产品:siRNA合成
[21]Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA.
发表于:Cancer Cell Int. 2019 PMCID: PMC6668142 IF=6.429
引用服务/产品:克隆构建、基因合成
[22]The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells.
发表于:Cancer Commun (Lond). 2021 PMCID: PMC7819566 IF=15.283
引用服务/产品:克隆构建、基因合成、环状RNA载体构建
[23]Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
发表于:Theranostics. 2021 PMCID: PMC7778598 IF=11.6
引用服务/产品:克隆构建、基因合成、sgRNA合成
[24]LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling.
发表于:Cell Death Dis. 2018 PMCID: PMC7778598 IF=7.109
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[25]DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.
发表于:Nucleic Acids Res. 2018 PMCID: PMC6009666 IF=19.16
引用服务/产品:克隆构建、基因合成
[26]Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming.
发表于:Cell Discov. 2019 PMCID: PMC6370818 IF=38.079
引用服务/产品:普通引物合成
[27]A humanized TCR retaining authentic specificity and affinity conferred potent anti‐tumour cytotoxicity.
发表于:Immunology. 2018 PMCID: PMC6099166 IF=7.215
引用服务/产品:Sanger测序
[28]HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5-WDR5-dependent transcriptional program.
发表于:Cancer Commun (Lond). 2022 PMCID: PMC9118058 IF=15.283
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[29]LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling.
发表于:Cancers (Basel). 2022 PMCID: PMC9657364 IF=6.575
引用服务/产品:克隆构建、基因合成
[30]The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway.
发表于:Int J Mol Sci. 2022 PMCID: PMC9570124 IF=6.208
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[31]PSMD2 contributes to the progression of esophageal squamous cell carcinoma by repressing autophagy.
发表于:Cell Biosci. 2023 PMCID: PMC10061715 IF=9.584
引用服务/产品:克隆构建、基因合成
[32]Anchoring super-enhancer-driven oncogenic lncRNAs for anti-tumor therapy in hepatocellular carcinoma.
发表于:Mol Ther. 2022 PMID: 36461633 IF=12.91
引用服务/产品:克隆构建、基因合成
[33]Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR-671-5p/LGALS3BP/NF-κB axis.
发表于:Cancer Sci. 2023 PMID: 37186007 IF=6.518
引用服务/产品:克隆构建、基因合成
[34]HHMMR promotes prostate cancer proliferation and metastasis via AURKAmTORC2E2F1 positive feedback loop.
发表于:Cell Death Discov. 2023 PMCID: PMC9905489 IF=7.109
引用服务/产品:克隆构建、基因合成
[35]HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway.
发表于:Adv Sci (Weinh). 2022 PMCID: PMC9811475 IF=17.521
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[36]PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells.
发表于:Cancer Res. 2023 PMID: 36480196 IF=13.312
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[37]Profle of chimeric RNAs and TMPRSS2‑ERG e2e4 isoform in neuroendocrine prostate cancer.
发表于:Cell Biosci. 2022 PMCID: PMC9463804 IF=9.58
引用服务/产品:克隆构建、基因合成
[38]RNA-binding protein MEX3A controls G1S transition via regulating the RBE2F pathway in clear cell renal cell carcinoma.
发表于:Mol Ther Nucleic Acids. 2021 PMCID: PMC8703191 IF=10.183
引用服务/产品:克隆构建、基因合成
[39]SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.
发表于:J Transl Med. 2023 PMCID: PMC10161564 IF=8.44
引用服务/产品:普通引物合成
[40]ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.
发表于:BMC Biol. 2020 PMCID: PMC7510086 IF=7.364
引用服务/产品:CRISPR sgRNA 文库服务
[41]CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
发表于:Mol Ther. 2021 PMCID: PMC7934638 IF=12.91
引用服务/产品:CRISPR sgRNA 文库服务
[42]Identification of Peptoniphilus vaginalis-Like Bacteria,Peptoniphilus septimus sp.nov., From Blood Cultures in a Cervical Cancer Patient Receiving Chemotherapy: Case and Implications.
发表于:Front Cell Infect Microbiol. 2022 PMCID: PMC9307962 IF=6.073
引用服务/产品:动植物基因组de novo 测序
[43]Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model.
发表于:Mol Ther Nucleic Acids. 2019 PMCID: PMC6849368 IF=10.183
引用服务/产品:RNA合成
[44]Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development.
发表于:LoS Genet. 2020 PMCID: PMC7605716 IF=6.02
引用服务/产品:小RNA 测序
[45]Efficient RNA drug delivery using red blood cell extracellular vesicles.
发表于:Nat Commun. 2018 PMCID: PMC6004015 IF=17.694
引用服务/产品:细胞株鉴定
[46]Precise A•T to G•C base editing in the zebrafish genome.
发表于:BMC Biol. 2018 PMCID: PMC6247682 IF=7.364
引用服务/产品:克隆构建、基因合成、环状RNA载体构建
[47]Genome-wide profiling of adenine base editor specificity by EndoV-seq.
发表于:Nat Commun. 2019 PMCID: PMC6325126 IF=17.694
引用服务/产品:克隆构建、基因合成
[48]Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis.
发表于:Molecular Cancer. 2019 PMCID: PMC652424 IF=44.144
引用服务/产品:克隆构建、基因合成、环状RNA载体构建
[49]circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway.
发表于:Molecular Cancer. 2020 PMCID: PMC6998850 IF=44.144
引用服务/产品:克隆构建、基因合成、环状RNA载体构建、细胞株鉴定
[50]A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease.
发表于:Cell. 2018 PMCID: PMC5935586 IF=66.85
引用服务/产品:Sanger测序、普通引物合成
[51]A CRISPR–Cas9-triggered strand displacement amplifification method for ultrasensitive DNA detection.
发表于:Nat Commun. 2018 PMCID: PMC6258682 IF=17.694
引用服务/产品:普通引物合成
[52]Quinoline Derivatives Kill Mycobacterium tuberculosis by Activating Glutamate Kinase.
发表于:Cell Chem Biol. 2019 PMID: 31204286 IF=9.039
引用服务/产品:克隆构建、基因合成
[53]A standard for near-scarless plasmid construction using reusable DNA parts.
发表于:Nat Commun. 2019 PMCID: PMC6650416 IF=17.694
引用服务/产品:普通引物合成
[54]Dual-CRISPR/Cas12a-Assisted RT-RAA for Ultrasensitive SARS-CoV‑2 Detection on Automated Centrifugal Microfluidics.
发表于:Anal Chem2022 PMID: 35775831 IF=8.008
引用服务/产品:普通引物合成
[55]Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer.
发表于:PLoS Pathog. 2023 PMCID: PMC9873182 IF=7.464
引用服务/产品:小RNA 测序
[56]Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2.
发表于:Int J Biol Sci. 2022 PMCID: PMC8935220 IF=10.75
引用服务/产品:小RNA 测序
[57]CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium.
发表于:Cancer Cell Int. 2022 PMCID: PMC8864845 IF=6.429
引用服务/产品:细胞株鉴定
[58]Two cGAS-like receptors induce antiviral immunity in Drosophila.
发表于:Nature. 2021 PMID: 34261128 IF=69.504
引用服务/产品:普通引物合成
[59]Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immunemodulatory chemotherapy.
发表于:Front Immunol. 2023 PMCID: PMC10043419 IF=8.786
引用服务/产品:Sanger测序
[60]Isolation and identifification of a salt-tolerant aerobic denitrifying bacterial strain and its application to saline wastewater treatment in constructed wetlands.
发表于:Bioresour Technol. 2019 PMID: 31301568 IF=11.889
引用服务/产品:菌种鉴定
[61]Effificient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor.
发表于:Cells. 2022 PMCID: PMC9776866 IF=7.666
引用服务/产品:Sanger测序
[62]The Atypical MAP Kinase MAPK15 Is Required for Lung Adenocarcinoma Metastasis via Its Interaction with NF-κB p50 Subunit and Transcriptional Regulation of Prostaglandin E2 Receptor EP3 Subtype.
发表于:Cancers (Basel). 2023 PMCID: PMC10000388 IF=6.575
引用服务/产品:普通引物合成、RNA合成、克隆构建、基因合成
[63]A Meloidogyne graminicola PectateLyase ls Involved in Virulence andActivation of Host DefenseResponses.
发表于:Front Plant Sci. 2021 PMCID: PMC8044864 IF=6.627
引用服务/产品:普通引物合成
[64]Eliminating predictable DNA off-targeteffects of cytosine base editor by using duaguiders including sgRNA and TALE.
发表于:Mol Ther. 2022 PMCID: PMC9263286 IF=12.91
引用服务/产品:基因合成、普通引物合成
[65]Microfluidic synthesis of manganese-alginate nanogels with self-supplyingHO2 capability for synergistic chemo/chemodynamic therapy andboosting anticancer immunity.
发表于:Chemical Engineering Journal.https://doi.org/10.1016/j.cej.2022.134926 IF=16.744
引用服务/产品:小RNA 测序
[66]HNF4A-BAP31-VDAC1 axis synchronously regulates cellproliferation and ferroptosis in gastric cancer.
发表于:Cell Death Dis. 2023 PMCID: PMC10256786 IF=9.685
引用服务/产品:基因合成
[67]SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition.
发表于:Commun Biol. 2023 PMCID: PMC10326080 IF=6.548
引用服务/产品:克隆构建、基因合成
[68]Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells .
发表于:Drug Resist Updat. 2023 PMID: 37423117 IF=24.3
引用服务/产品:克隆构建、基因合成
[69]Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery.
发表于:Nat Cell Biol. 2023 PMID: 37322289 IF=28.213
引用服务/产品:siRNA合成
[70]Decrotonylation of AKT1 promotes AKT1 phosphorylation and activation during myogenic differentiation.
发表于:J Adv Res. 2023 PMCID: PMC10403674 IF=10.7
引用服务/产品:克隆构建、基因合成
[71]Upregulated LncRNA H19 Sponges MiR-106a- 5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2- Dependent Pathway.
发表于:Arterioscler Thromb Vasc Biol. 2023 PMID: 37409531 IF=10.514
引用服务/产品:克隆构建、基因合成、siRNA 转染试剂
[72]UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.
发表于:Cell Death Dis. 2023 PMCID: PMC10329682 IF=9.685
引用服务/产品:克隆构建、基因合成
[73]Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure.
发表于:J Tissue Eng. 2023 PMCID: PMC10510347 IF=8.2
引用服务/产品:血卡、千血斑基因组DNA提取试剂
[74]FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson’s disease via m6A-dependent regulation of ATM mRNA.
发表于:J Transl Med. 2023 PMCID: PMC10515429 IF=7.4
引用服务/产品:siRNA合成
[75]Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
发表于:J Transl Med. 2023 PMCID: PMC10536727 IF=7.4
引用服务/产品:克隆构建、基因合成
[76]Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
发表于:Cell Death Dis. 2023 PMCID: PMC10427658 IF=9.685
引用服务/产品:克隆构建、基因合成
[77]The APCC E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer.
发表于:Cell Death Dis. 2023 PMCID: PMC10423259 IF=9.685
引用服务/产品:克隆构建、基因合成
[78]Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma.
发表于:Adv Res. 2023 PMCID: PMC10491973 IF=10.7
引用服务/产品:克隆构建、基因合成、shRNA 设计及构建
[79]Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
发表于:Elife. 2023 Dec 11 PMCID: PMC10712958 IF=8.7
引用服务/产品:细胞株鉴定
[80]Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis
发表于:CNS Neurosci Ther. 2024 Mar PMCID: PMC10958405 IF=7.035
引用服务/产品:siRNA合成
[81]CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2HO-1 axis, regulating CD8+T cell response
发表于:J Transl Med. 2024 Mar 14 PMCID: PMC10938737 IF=8.44
引用服务/产品:miRNA合成
[82]Combined therapy of CAR-IL-15IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor efect against gastric cancer
发表于:J Transl Med. 2024 Feb 18 PMCID: PMC10874561 IF=8.44
引用服务/产品:转录组测序
[83]Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration
发表于:Commun Biol. 2024 Mar 14 PMCID: PMC10940657 IF=6.548
引用服务/产品:siRNA合成
[84]Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non-Small-Cell Lung Carcinoma
发表于:Adv Sci (Weinh). 2024 Jan PMCID: PMC10767400 IF=17.521
引用服务/产品:克隆构建、基因合成
[85]Heterologously Expressed Cellobiose Dehydrogenase Acts as Efficient Electron-Donor of Lytic Polysaccharide Monooxygenase for Cellulose Degradation in Trichoderma reesei
发表于:Int J Mol Sci. 2023 Dec 6 PMCID: PMC10743782 IF=6.208
引用服务/产品:克隆构建、基因合成
[86]Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
发表于:iScience. 2023 Dec 8 PMCID: PMC10776932 IF=6.107
引用服务/产品:克隆构建、基因合成、引物合成
[87]SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids
发表于:Antioxid Redox Signal . 2023 Jul PMCID: PMC10620438 IF=7.468
引用服务/产品:siRNA合成
[88]Upregulated TIMP1 facilitates and coordinates myometrial contraction by decreasing collagens and cell adhesive capacity during human labor
发表于:Mol Hum Reprod . 2023 Sep 30 PMCID: PMC10581194 IF=4.518
引用服务/产品:siRNA合成
[89]VPS35 promotes gastric cancer progression through integrinFAKSRC signalling-mediated IL-6STAT3 pathway activation in a YAP-dependent manner
发表于:Oncogene. 2024 Jan PMCID: PMC10774127 IF=8.756
引用服务/产品:克隆构建
[90]A Biomimetic Multifunctional Nanoframework for Symptom Relief and Restorative Treatment of Acute Liver Failure
发表于:ACS Nano. 2024 Jan 31 PMCID: PMC10883031 IF=17.1
引用服务/产品:转录组测序